18 August 2018


THE OFFICIAL BOKONE BOPHIRIMA GOVERNMENT NEWSPAPER

SAHPRA warns of pain-relieving drugs danger 

by: SAnews.gov.za   date: 03 August 2018

The South African Health Products Regulatory Authority (SAHPRA) has warned the public about the risk of harmful effects when using non-steroidal anti-inflammatory drugs (NSAIDs).

NSAIDs are a group of medicines, including aspirin, ibuprofen, diclofenac, indomethacin, ketorolac, sulindac, lornoxicam, meloxicam, piroxicam, tenoxicam, naproxen, mefenamic acid, celecoxib, rofecoxib, parecoxib and valdecoxib.

The medicines are used to reduce pain and fever. They are available both over-the-counter (OTC) and on prescription upon consultation with a doctor.
They are also available both as single medicines and in combination with other medicines.

While considered safe when taken as directed, SAHPRA warned that NSAIDs can cause stomach bleedings, may reduce kidney function and may occasionally lead to heart attack or stroke.

“These risks are higher with higher doses and/or longer than recommended period of use of NSAIDs and in patients who have pre-existing stomach problems, or have heart or kidney diseases. If you take low-dose aspirin for protection against heart attack and stroke, be advised that some NSAIDs can interfere with that protective effect.

“If you have heart disease or high blood pressure, consult a health care provider before using an NSAID. Please inform your health care provider of any existing heart condition or known kidney problems or pre-existing stomach condition when seeking treatment,” SAHPRA said.

SAHPRA added that prescription NSAIDs were an important treatment for the symptoms of many debilitating conditions, including osteoarthritis, rheumatoid arthritis, gout and other rheumatological and painful conditions.

“OTC NSAIDs are used to temporarily reduce fever and to treat minor aches and pains such as headaches, toothaches, backaches, muscular aches, tendonitis and strains,” it said. 

Consumers are urged to read the patient information leaflet for both OTC and prescription medicines as it provides important safety information.

SAHPRA advises consumers to seek medical help if they experience stomach bleeding or symptoms that might signal heart problems or stroke, such as chest pain, trouble breathing, sudden weakness in one part or side of the body or sudden slurred speech while on NSAIDs.

Health professionals in South Africa are also urged to report any adverse reactions to the National Adverse Drug Event Monitoring Centre at (021) 4471618 or SAHPRA pharmacovigilance office on (012) 395 9133 or use the reporting form which can be accessed at http://www.mccza.com/documents/14ed44a46.04_ARF1_Jul16_v4.pdf and emailed to adr@health.gov.za